Quarter snapshot

Baker Bros. Advisors

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Quarter: Q1 2026
Filed: 2026-05-15
Portfolio value: $17,415,689,929
Positions: 84
Sources: 13F on EDGAR

history	Ticker	Change	% of portfolio	Shares	Value
≡	ACRV	SOLD	—	—	—
≡	KALA	SOLD	—	—	—
≡	VIR	SOLD	—	—	—
≡	FDMT	SOLD	—	—	—
≡	NUVL	SOLD	—	—	—
≡	VTYX	SOLD	—	—	—
≡	BCRX	SOLD	—	—	—
≡	TERN	SOLD	—	—	—
≡	RARE	SOLD	—	—	—
≡	SRZNW		0.0%	833,333	$13,333
≡	TYRA		0.0%	10,607	$406,248
≡	ALGS		0.0%	83,055	$617,099
≡	SANA		0.01%	310,483	$894,191
≡	SKYE	+9%	0.01%	1,575,243	$968,144
≡	TCRX		0.02%	2,784,792	$2,812,640
≡	VSTM	NEW	0.02%	584,757	$3,099,212
≡	LBRX		0.03%	200,000	$4,932,000
≡	SGMT		0.03%	952,996	$4,979,404
≡	TARA		0.03%	971,614	$5,062,109
≡	EIKN	NEW	0.03%	555,555	$5,877,772
≡	VTVT		0.03%	148,314	$5,882,133
≡	WVE	+139%	0.03%	822,638	$5,964,126
≡	ABSI		0.04%	2,134,803	$6,404,409
≡	MPLT		0.04%	364,705	$7,414,453
≡	RCUS	+54%	0.05%	415,621	$8,977,414
≡	PHVS		0.06%	375,000	$10,593,750
≡	BNTX	−68%	0.06%	119,743	$10,642,758
≡	SERA		0.06%	5,498,170	$11,161,285
≡	RLAY		0.07%	1,160,117	$11,543,164
≡	CMPS	NEW	0.07%	2,344,720	$12,966,302
≡	XNCR		0.08%	1,102,106	$13,291,398
≡	DYN		0.08%	813,449	$14,747,830
≡	SION		0.09%	400,000	$16,036,000
≡	GENB	NEW	0.1%	1,423,602	$17,795,025
≡	AKTS	NEW	0.1%	996,351	$17,824,719
≡	TSHA		0.1%	4,004,756	$17,901,259
≡	CERS		0.1%	10,008,345	$18,215,188
≡	ARGX		0.11%	25,174	$18,383,314
≡	CTNM		0.11%	1,420,838	$18,556,144
≡	TECX	−33%	0.11%	607,788	$18,786,727
≡	EVMN	NEW	0.11%	847,390	$19,481,496
≡	NGNE		0.11%	991,691	$19,992,491
≡	CLDX		0.12%	665,370	$21,105,536
≡	XENE		0.12%	370,208	$21,527,595
≡	IMCR	−68%	0.13%	734,397	$22,142,070
≡	IRON	+4%	0.13%	349,657	$22,357,069
≡	JBIO		0.13%	1,641,137	$23,057,975
≡	CTMX	+17%	0.13%	4,975,826	$23,386,382
≡	CNTA		0.15%	670,751	$26,642,230
≡	DSGN	+16%	0.16%	2,585,978	$27,514,806
≡	DBVT		0.18%	1,461,425	$30,529,168
≡	PRLD		0.2%	10,123,824	$34,623,478
≡	ELVN	+234%	0.2%	905,191	$35,483,487
≡	VRDN		0.22%	1,971,678	$38,566,022
≡	MIRM	NEW	0.24%	445,975	$41,199,171
≡	ALMS	+29%	0.25%	2,012,500	$44,335,375
≡	RAPP		0.28%	1,547,090	$48,408,446
≡	SYRE		0.29%	1,000,000	$50,440,000
≡	BCYC		0.29%	10,885,357	$50,508,056
≡	TRDA		0.37%	5,072,730	$64,017,853
≡	GPCR		0.4%	1,432,529	$69,047,898
≡	GLUE		0.41%	4,345,736	$71,487,357
≡	DNTH	+8%	0.41%	852,164	$71,513,603
≡	DNLI		0.41%	3,731,695	$71,648,544
≡	NRIX		0.41%	4,658,556	$72,207,618
≡	Unmapped CUSIP		0.43%	30,750,000	$74,868,563
≡	REPL		0.49%	11,045,336	$84,496,820
≡	CRNX	+43%	0.49%	2,351,465	$85,405,209
≡	ABVX		0.56%	875,796	$97,519,885
≡	ABCL	+10%	0.61%	30,275,938	$105,663,024
≡	IMTX	−10%	0.62%	10,916,693	$107,420,259
≡	STOK		0.62%	3,336,697	$108,642,854
≡	ARWR	−8%	0.72%	1,992,783	$124,947,494
≡	IDYA	+9%	0.76%	3,946,515	$131,497,880
≡	ROIV	−12%	0.77%	4,867,723	$134,835,927
≡	IMVT		0.78%	5,457,881	$135,573,764
≡	KNSA		0.78%	2,826,246	$136,083,745
≡	IONS	+14%	0.88%	2,047,727	$153,763,820
≡	EWTX		1.19%	6,575,940	$207,142,110
≡	GRAL	+93%	1.2%	4,028,614	$208,198,772
≡	ALKS		2.03%	10,012,267	$354,033,761
≡	RYTM		2.8%	5,604,483	$487,421,887
≡	PRAX	+56%	3.24%	1,753,198	$564,862,864
≡	SMMT		3.96%	36,391,063	$689,974,554
≡	KYMR		4.14%	8,657,242	$721,061,686
≡	KOD		4.36%	19,919,186	$759,319,370
≡	CELC		5.19%	7,915,792	$903,508,499
≡	RVMD	+1%	5.34%	9,555,357	$929,258,468
≡	A		5.48%	42,896,690	$954,880,319
≡	MDGL		6.44%	2,141,701	$1,121,116,222
≡	INSM	+13%	6.97%	7,421,111	$1,213,500,071
≡	ONC		15.0%	8,799,053	$2,613,054,769
≡	INCY	+0%	16.62%	30,744,412	$2,893,664,057