Fund portfolio

Baker Bros. Advisors

Quarter: Q1 2026
Filed: 2026-05-15
Portfolio value: $17,415,689,929
Positions: 84
Source: 13F on EDGAR ↗

Ticker	Change	% of portfolio	Shares	Value
INCY history	+0%	16.62%	30,744,412	$2,893,664,057
ONC history		15.0%	8,799,053	$2,613,054,769
INSM history	+13%	6.97%	7,421,111	$1,213,500,071
MDGL history		6.44%	2,141,701	$1,121,116,222
A history		5.48%	42,896,690	$954,880,319
RVMD history	+1%	5.34%	9,555,357	$929,258,468
CELC history		5.19%	7,915,792	$903,508,499
KOD history		4.36%	19,919,186	$759,319,370
KYMR history		4.14%	8,657,242	$721,061,686
SMMT history		3.96%	36,391,063	$689,974,554
PRAX history	+56%	3.24%	1,753,198	$564,862,864
RYTM history		2.8%	5,604,483	$487,421,887
ALKS history		2.03%	10,012,267	$354,033,761
GRAL history	+93%	1.2%	4,028,614	$208,198,772
EWTX history		1.19%	6,575,940	$207,142,110
IONS history	+14%	0.88%	2,047,727	$153,763,820
KNSA history		0.78%	2,826,246	$136,083,745
IMVT history		0.78%	5,457,881	$135,573,764
ROIV history	−12%	0.77%	4,867,723	$134,835,927
IDYA history	+9%	0.76%	3,946,515	$131,497,880
ARWR history	−8%	0.72%	1,992,783	$124,947,494
STOK history		0.62%	3,336,697	$108,642,854
IMTX history	−10%	0.62%	10,916,693	$107,420,259
ABCL history	+10%	0.61%	30,275,938	$105,663,024
ABVX history		0.56%	875,796	$97,519,885
CRNX history	+43%	0.49%	2,351,465	$85,405,209
REPL history		0.49%	11,045,336	$84,496,820
15102KAA8 history		0.43%	30,750,000	$74,868,563
NRIX history		0.41%	4,658,556	$72,207,618
DNLI history		0.41%	3,731,695	$71,648,544
DNTH history	+8%	0.41%	852,164	$71,513,603
GLUE history		0.41%	4,345,736	$71,487,357
GPCR history		0.4%	1,432,529	$69,047,898
TRDA history		0.37%	5,072,730	$64,017,853
BCYC history		0.29%	10,885,357	$50,508,056
SYRE history		0.29%	1,000,000	$50,440,000
RAPP history		0.28%	1,547,090	$48,408,446
ALMS history	+29%	0.25%	2,012,500	$44,335,375
MIRM history	NEW	0.24%	445,975	$41,199,171
VRDN history		0.22%	1,971,678	$38,566,022
ELVN history	+234%	0.2%	905,191	$35,483,487
PRLD history		0.2%	10,123,824	$34,623,478
DBVT history		0.18%	1,461,425	$30,529,168
DSGN history	+16%	0.16%	2,585,978	$27,514,806
CNTA history		0.15%	670,751	$26,642,230
CTMX history	+17%	0.13%	4,975,826	$23,386,382
JBIO history		0.13%	1,641,137	$23,057,975
IRON history	+4%	0.13%	349,657	$22,357,069
IMCR history	−68%	0.13%	734,397	$22,142,070
XENE history		0.12%	370,208	$21,527,595
CLDX history		0.12%	665,370	$21,105,536
NGNE history		0.11%	991,691	$19,992,491
EVMN history	NEW	0.11%	847,390	$19,481,496
TECX history	−33%	0.11%	607,788	$18,786,727
CTNM history		0.11%	1,420,838	$18,556,144
ARGX history		0.11%	25,174	$18,383,314
CERS history		0.1%	10,008,345	$18,215,188
TSHA history		0.1%	4,004,756	$17,901,259
AKTS history	NEW	0.1%	996,351	$17,824,719
GENB history	NEW	0.1%	1,423,602	$17,795,025
SION history		0.09%	400,000	$16,036,000
DYN history		0.08%	813,449	$14,747,830
XNCR history		0.08%	1,102,106	$13,291,398
CMPS history	NEW	0.07%	2,344,720	$12,966,302
RLAY history		0.07%	1,160,117	$11,543,164
SERA history		0.06%	5,498,170	$11,161,285
BNTX history	−68%	0.06%	119,743	$10,642,758
PHVS history		0.06%	375,000	$10,593,750
RCUS history	+54%	0.05%	415,621	$8,977,414
MPLT history		0.04%	364,705	$7,414,453
ABSI history		0.04%	2,134,803	$6,404,409
WVE history	+139%	0.03%	822,638	$5,964,126
VTVT history		0.03%	148,314	$5,882,133
EIKN history	NEW	0.03%	555,555	$5,877,772
TARA history		0.03%	971,614	$5,062,109
SGMT history		0.03%	952,996	$4,979,404
LBRX history		0.03%	200,000	$4,932,000
VSTM history	NEW	0.02%	584,757	$3,099,212
TCRX history		0.02%	2,784,792	$2,812,640
SKYE history	+9%	0.01%	1,575,243	$968,144
SANA history		0.01%	310,483	$894,191
ALGS history		0.0%	83,055	$617,099
TYRA history		0.0%	10,607	$406,248
SRZNW history		0.0%	833,333	$13,333
RARE history	SOLD	—	—	—
TERN history	SOLD	—	—	—
BCRX history	SOLD	—	—	—
VTYX history	SOLD	—	—	—
NUVL history	SOLD	—	—	—
FDMT history	SOLD	—	—	—
VIR history	SOLD	—	—	—
KALA history	SOLD	—	—	—
ACRV history	SOLD	—	—	—